KMT2C and neoplasm: Similarly, Kmt2c suppression also attenuated MYC-induced apoptosis, as shown by tumor histology and apoptosis by TUNEL assay (Negoescu et al., 1997), 5 days after hydrodynamic delivery of transposon vectors encoding Myc together with GFP-linked shRNAs targeting Kmt2c (or Renilla luciferase as a control; Figure 5A and B).