Colitis was induced in HNF1A-AS1+/+, HNF1A-AS1intestine+/–, and HNF1A-AS1intestine–/–mice by Dextran Sodium Sulphate–induced (DSS-induced) colitis that was added to water at a concentration of 2.5% (w/v) for 5 days, followed by 6 days of washout. The gene discussed is HNF1A; the disease is colitis.