Regarding innate immune cells, the frequency of CD11b+CSF1R+ monocytes was constant among the groups (Supplemental Figure 11A), whereas we observed a relevant decrease in CSF1R+PD-L1+ monocytes in the anti–miR-93-5p–treated and sham-operated mice compared with the sepsis mouse model mice treated with scrambled control miRNA (P < 0.001 for both comparisons) and control mice (P < 0.01 and P < 0.05, respectively) (Figure 4D). Here, CD274 is linked to Sepsis.