KEGG pathway analysis revealed the following top 10 pathways: Hematopoietic cell lineage, Legionellosis, Pantothenate and CoA biosynthesis, Inflammatory bowel disease, Leishmaniasis, Drug metabolism-other enzymes, Th1 and Th2 cell differentiation, Staphylococcus aureus infection, Viral protein interaction with cytokine and cytokine receptor and Th17 cell differentiation. The gene discussed is IL18R1; the disease is leishmaniasis.