Activated microglia in MS and EAE are associated with the production of several pro-inflammatory cytokines (IL-6, IL-1β, IL-18, IL-12, IL-23, TNF-α) and chemokines (CCL2, CCL3, CCL4, CCL5, CCL7, CCL12) (135). The gene discussed is TNF; the disease is myeloid sarcoma.