Host protection against fungal keratitis- ↓ Clinical scores, PMN infiltration, and fungal load in eyes of mice- ↓ Inflammatory responses in response to fungal keratitis- ↓ IL-1β and CXCL1 in HCECs- ↓ IL-1β, IL-8, and IL-6 in infected corneasActivation of Nrf2/HO-1 signaling pathway- ↑ Nrf2 and/HO-1 expression in DI-treated corneas of mice- ↑ Nuclear Nrf2 accumulation in HCECs. Here, NFE2L2 is linked to fungal keratitis.