Both thrombocytopenia and thrombosis were prevented with FcγRIIa inhibition via IV.3, but only thrombosis and not thrombocytopenia was abrogated by NETosis inhibitor GSK484 or the genetic knockout of peptidylarginine deiminase 4 (PAD4) in the FcγRIIa+/hPF4+ mice (132). Here, PADI4 is linked to deep vein thrombosis.