The LASSO logistics regression and SVM-RFE algorithms (Figures 4(a), 4(b), and 4(c)) revealed that 19 rejection-related genes involved in ccRCC occurrence, including RAC2, PLA1A, NLRC5, LAPTM5, TYROBP, TAP1, CCL8, IRF1, GBP2, PSMB9, FCN1, GBP1, GPR171, ITK, PLAC8, CCL5, ADAMDEC1, IDO1, and CXCL9 (Figures 4(d) and 4(e)). The gene discussed is IRF1; the disease is nonpapillary renal cell carcinoma.