As some studies have indicated, miR-200b silences angiogenesis and is correlated with the metastatic cascade in breast tumor, and we present that mir-200b-3p is also deregulated in endothelial cells derived from this pathological tissue (Amorim et al., 2019; Chen et al., 2022) The bioinformatics analysis shows that VEGFA and KDR1 (VEGFA receptor) may be mir-200b-3p target genes. The gene discussed is VEGFA; the disease is breast neoplasm.