TNF and anxiety disorder: Inflammation and immune processes have been associated with anxiety disorders (Felger, 2018; Wang et al., 2018), including elevated inflammatory markers in the cerebrospinal fluid and circulating concentrations of inflammatory cytokines, chemokines, and acute phase proteins, such as TNF-α, reactant C-reactive protein, and interleukine-6 (Capuron and Miller, 2011; Michopoulos et al., 2017).