The GSEA, showed that the group of LB BRCA patients with high expression of LINC00426 is significatively enriched (nominal p-value < 0.05 and FDR <25%) with eight immune-related gene sets (IL2-STAT5 signaling, complement, inflammatory response, allograft rejection, IL6-JAK-STAT signaling, interferon gamma response, TNFα signaling via NFκB and interferon alpha response) and seven cancer-related gene sets (KRAS signaling up, apoptosis, coagulation, epithelial-mesenchymal transition, PI3K-AKT-mTOR, apical junction and apical surface) (Table 4). This evidence concerns the gene AKT1 and invasive breast carcinoma.