Tissue radiation generates ROS and kinase activation associated with DNA damage, resulting in the expression of NK cell-activating ligands (NKALs) that activate and secrete the chemokines XCL1, FLT3LG, and CCL5 to recruit dendritic cells (DCs), which, induces tumor suppression in the tumor microenvironment [7]. The gene discussed is XCL1; the disease is neoplasm.