IL17A and psoriasis: In this study, by employing the imiquimod-induced psoriasis murine model, the authors found that the activated transient receptor potential V1+ nerves innervating the skin are required to promote IL-23 production in dermal DCs, which, in turn, can stimulate dermal gamma-delta T cells to secrete IL-17A, IL-17F, and IL-22, resulting in the recruitment of more neutrophils to the skin and excessive keratinocyte proliferation.