Dextran sodium sulfate (DSS)-treated C57/BL6 mice as a murine model of colitis and TNF∆ARE/+ mice as a murine model of Crohn ́s disease-like ileitis addressed the anti-inflammatory properties of recombinant human Lf (VEN-120) administered at 500 mg/kg/14 days by gavage [63]. The gene discussed is LTF; the disease is colitis.