TNF and prostate carcinoma: By contrast, tectochrysin has been demonstrated to induce apoptosis in prostate cancer cells by affecting the TNF-α-related apoptosis-inducing ligand and phosphatidylinositol 3-kinase/protein kinase B signaling pathways, suppressing NF-κB activity, and increasing the expression levels of death receptors in colon cancer cells [8,18].