HTR1A and major depressive disorder: Bearing in mind the significant role of the serotonin system, especially 5-HT1A and 5-HT7 receptor modulation, in depression [9], we decided to evaluate the antidepressant-like effect of the tested compound in the forced swim and tail suspension tests in mice, which are two common behavioral tests to assess the antidepressant-like activity of novel compounds.