Moreover, we found significant correlations between ICOS mRNA with AXL and MITF mRNA expression in the melanoma cell lines from the GDSC (ICOS/AXL: ρ = -0.457, P = 0.008; ICOS/MITF: ρ = 0.441, P = 0.010; N = 33). This evidence concerns the gene MITF and melanoma.