CSF1R and Hereditary diffuse leukoencephalopathy with axonal spheroids and pigmented glia: To further examine the possible mechanisms by which minocycline exposure led to beneficial therapeutic effects on behavioral and pathological deficits of Csf1r+/− ALSP model mice, we collected cerebral samples from Csf1r+/+ or Csf1r+/− male mice treated or not with minocycline for RNA-seq analysis.