In addition, we evaluated the diagnostic value of plasma versican or plasma exosomal versican in patients with NSCLC, and the findings revealed that both were superior to that of NSE, CEA, CYFRA21-1, and SCC in the diagnosis of NSCLC, and that they were superior to that of NSE and SCC in the diagnosis of NSCLC with metastasis. Here, CEACAM5 is linked to non-small cell lung carcinoma.