The risk score of each patient was calculated using the following formula based on their regression coefficient of the expression levels of these 3 markers (Supplementary Table 4): risk score = 0.003 × Hscore of FHL3 in tumor -0.006× Hscore of GGA1 in tumor +0.004× Hscore of TGFBI in stromal. This evidence concerns the gene TGFBI and neoplasm.