RAG2 and neoplasm: To assess the role of antigen-specific CD8 T cells in this local rejection, we implanted KPP-eGFP tumours in RAG2-deficient mice and reconstituted the mice with naive tdTomato+ T cells either from mice that contain a polyclonal population of T cells, or OT-I mice, which contain a monoclonal population of ovalbumin-specific CD8 T cells (Supplementary Video 1).