CHRNA1 and nervous system disorder: Genes of Neurologic Disease were predominated by ion channel representation (KCNQ2, SCN9A, KCNC1, KCNA4, CHRNA1, GRIA1, NPY2R), whereas Inflammatory Response embodied a mêlée of chemokines/cytokines (CXCL3, CXCR6), immune-specific receptors (CD180, CD22, CD5L), and matrix metalloproteinases (MMP3, MMP12).