Peptides that can block the PD-1/PD-L1 interaction and restore T cell activity against tumor cells have been identified94–101; these include peptide-57 (F(NMeAla)NPHLSWSW(NMeNle)(NMeNle)RCG), CLP001 (HYPERPHANQAS)/CLP002 (WHRSYYTWNLNT), and PD-L1Pep-1 (CLQKTPKQC)/PD-L1Pep-2 (CVRARTR) peptides. Here, CD274 is linked to neoplasm.