AOC1 and cancer: Since KEGG analysis indicated that LINC00839 might exert influence on transcriptional misregulation in cancer, we performed ChIP assays and detected that LINC00839 increased the occupancy of TAF15 to promoter region of AOC1. Previous studies demonstrated that lncRNA could promote FET proteins to oligomerize and then activate the direct binding of FET protein and RNA Pol II (52, 53, 54).