Results revealed a significant, though modest, shift in the size distribution of 6E10+ plaques between groups (Kolmogorov-Smirnov test; p = 0.049), with AD p38KO mice having larger plaques (median = 88.22 μm2) compared to AD p38+/+ animals (median = 82.39 μm2) (Fig 4F). The gene discussed is MAPK14; the disease is Alzheimer disease.