HMGB1 and hyperandrogenism: In sensitivity analyses conducted within the whole cohort of women with PCOS, serum HMGB1 levels did not differ according to the clinical phenotypes of PCOS or the presence vs absence of each element used for this diagnosis (i.e. presence vs absence of either clinical or biochemical hyperandrogenism, altered vs preserved ovulatory capacity, or presence vs absence of PCOm) (data not shown).