KLK3 and pachyonychia congenita: The multivariate analysis showed that age {Odds ratio (OR): 1.91, 95% confidence interval (CI): 1.64-2.22, p-value < 0.001}, PSA (OR: 1.08, 95% CI: 1.04-1.11, p-value < 0.001), total cholesterol (OR: 0.96, 95% CI: 0.92-0.99, p-value = 0.011) and triglyceride level (OR: 1.05, 95% CI: 1.03-1.07, p-value < 0.001) were associated with PC risk (Figure 1).