To examine the role of SP-A in pneumonia-induced sepsis, bacterial dynamic changes were compared in the lungs of WT, KO, and hTG mice at 0, 12, 24, 36, and 48h after intratracheal inoculation of bioluminescent P. aeruginosa by In vivo imaging method (Figure 2A). The gene discussed is SFTPA2; the disease is Sepsis.