A wide variety of cardiovascular diseases after SARS-Cov-2 infection have been reported, including myocarditis (Boukhris et al., 2020; Irabien-Ortiz et al., 2020; Sawalha et al., 2021), and the NLRP3 inflammasome may be activated by SARS-Cov-2 infection and participate in the progression of Corona Virus Disease 2019 (COVID-19)-related myocarditis. The gene discussed is NLRP3; the disease is COVID-19.