In stratified analysis by CIN subgroups, a statistically significant association between IL-2 levels and prevalence of CIN I was observed (1st versus 4th quartile: OR = 1.32; 95% CI: 1.01 1.73) while an inverse association was observed for CIN II/III (1st versus 4th quartile: OR = 3.53; 95% CI: 2.26, 5.52). The gene discussed is IL2; the disease is cervical squamous intraepithelial neoplasia.