PIK3CA and cancer: The scatter plot analysis results of KEGG enrichment analysis show that according to the number of enriched target genes with significant differences, the top ten are pathways in cancer, MAPK signaling pathway, Ras signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, mTOR signaling pathway, human cytomegalovirus infection, autophagy – animal, human T-cell leukemia virus 1 infection and AMPK signaling pathway (Figure 2B).