Neurological manifestations in CA-TTR patients include sensorimotor and autonomic neuropathy, which predominantly involves small non-myelinated nerve fibers (Algalarrondo et al., 2106; Goldstein, 2016; Griffin et al., 2021; Kaur et al., 2021; Kharoubi et al., 2021; Tozza et al., 2021). The gene discussed is TTR; the disease is autonomic neuropathy.