Our results showed significant and inverse associations between an increased concentration of plasma FABP4 with both HF and LF HRV (p for trend = 0.007 and 0.017, respectively); furthermore, in multiple linear regression model, we found that FABP4 was positively associated with BMI, diabetes mellitus, hypertension, SBP, LDL-C, triglycerides, creatinine, and FABP3. This evidence concerns the gene FABP4 and hypertensive disorder.