TNF and preeclampsia: Statins have been reported to attenuate inflammatory markers [e.g., high-sensitivity C-reactive protein (hs-CRP), interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α)], as well as improve imbalance in the T helper cell type 1 (Th1) over Th2 cytokine responses observed in preeclampsia (8).