CXCL14 expression in cells can be governed by genetic modulation in terms of methylation state and single-nucleotide polymorphisms (SNPs), which may have a bearing on its pathophysiologic actions, as recently shown by us in case of junctional adhesion molecule-A (F11R) in patients with coronary artery disease (CAD) [9]. The gene discussed is CXCL14; the disease is coronary artery disorder.