Furthermore, pathway analysis using the Kyoto Encyclopedia of Genes and Genomes (KEGG) database suggested that these edited genes were for pathways of relevance to DLBCL (like the apoptosis/p53 signaling pathway or the NF-κB signaling pathway - Figure 2A) but also for pathways that have not been associated with DLBCL (like the RIG-I-like Receptor (RLR) signaling pathway; Figure 2A). The gene discussed is TP53; the disease is diffuse large B-cell lymphoma.