Notably, these DEPs including Fads2, Fgb, Cypla2, Cyp2e1, Cfb, Serping1, Fgg, Etnppl, Agt, Hsd3b5, Gnmt, A2m, Pck1, Stat3, Ptpn1, Scd1, Slc2a1, and Uox were key genes in liver sepsis, which maybe associated with inflammation in sepsis. This evidence concerns the gene SERPING1 and Sepsis.