Among these, selective essentiality for GATA3 was only observed for high-NE-score neuroblastoma cell lines but not SCLC cell lines (Fig. 7F and G), whereas BCAR1 appears to be a shared vulnerability for low-NE-score cell lines in both neuroblastoma and SCLC (Fig. 7H and I). Here, GATA3 is linked to small cell lung carcinoma.