In the neuroblastoma datasets, we investigated, the previously reported prognostic factors—age, MYCN amplification, and INSS stage 4 disease—were consistently associated with worse overall survival (Supplementary Fig. S2A–S2C), but we did not observe a significant difference in NE scores in groups stratified by these factors (Supplementary Fig. S2D and S2F). The gene discussed is MYCN; the disease is neuroblastoma.