A previous study showed that a missense variant, which leads to a change of a proline to a serine, in the gene encoding HIF1A is associated with the expression of HIF-1α protein in breast cancer.30 However, our study did not support that variations in rs2301113 and rs2057482 play a role in protein expression in OTM and might be not involved in the genetic predisposition for “slow” or “fast” mover phenotypes. Here, HIF1A is linked to breast carcinoma.