IFNA1 and Hutchinson-Gilford progeria syndrome: The robust activation of IFN response along with the ISGs activation in the absence of IFN expression was also observed in a previous study on the premature aging disease, Hutchinson‐Gilford progeria syndrome (HGPS) (Kreienkamp et al., 2018), suggesting that the upregulation of ISGs in senescing A‐T fibroblasts, similar to HGPS fibroblasts, is probably a cell‐intrinsic and IFN‐independent process.