PECAM1 and Alzheimer disease: We confirmed previous human findings demonstrating that blood levels of LPS [44], soluble CAMs (i.e., VCAM-1, PECAM-1, P-Selectin, E-Selectin, NCAM, ICAM-1) [27, 45–49], IL1β, IL6, TNFα [30] are increased in AD patients compared with controls.