Interestingly, we identified a positive correlation between α-SMA+ CAF density and the number of M2-like CD163+ MØs (R = 0.54; P = 0.047) that enhance tumor progression, as well as immunologic effector cells that are presumably tumor suppressive, such as CD4+ (R = 0.74; P = 0.0067) and CD8+ (R = 0.56; P = 0.0038) T cells, and a weak correlation with granzyme B+ (R = 0.36; P = 0.14) immune cells (Fig. 1B). This evidence concerns the gene ACTA1 and neoplasm.