In addition to being expressed on the tumor surface and participating in immune escape, PD-L1 is also expressed on the surface of antigen presenting cells (DC cells, macrophages, etc.)and vascular endothelial cells under the stimulation of IFN-γ, which indicates that the infiltration of tumor cells, DC cells or macrophages increases in the lymph node metastasis group. This evidence concerns the gene CD274 and neoplasm.