The results showed that the expression levels of the activating receptors (NKG2D, NKp46, and NKp30) in the peripheral blood of HCC patients were not significantly different between D0 and D7 but were increased from D0 to M1 (all P < 0.05) (Fig. 2B-D). This evidence concerns the gene KLRK1 and hepatocellular carcinoma.