Supporting GO and KEGG analyses, gene set enrichment analyses (GSEA)34 also revealed that the upregulated DEGs in T-47D FAAH KO cells were significantly associated to highly aggressive signatures such as those of epithelial-to-mesenchymal transition (EMT)35, BC metastasis to the lungs36 (Supplementary Figs. 8d, e), basal and mesenchymal traits37, MaSC populations38, and van’t Veer poor prognosis BC signature25 (Fig. 5d), which is used clinically to identify BC patients at a greater risk of developing metastatic disease. Here, FAAH is linked to breast cancer.