PFKFB3 and pancreatic adenocarcinoma: Furthermore, strong correlations between PFKFB3 expression and pathological stage were observed in endocervical adenocarcinoma (CESC), THCA, pancreatic adenocarcinoma (PAAD), testicular germ cell tumors (TGCT), and Ovarian serous cystadenocarcinoma (OV, all P < 0.05, Figure 1B and Supplementary Figure 3).