PFKFB3 and adrenal cortex carcinoma: We explored the survival prognosis value of PFKFB3 using Kaplan-Meier, the overall survival (OS) results show that high expression of PFKFB3 was significantly correlated to the poor OS for patients with adrenocortical carcinoma (ACC) (HR = 2.91, logrank p = 0.0087), KIRP (HR = 2.14, logrank p = 0.0168), STAD (HR = 1.47, logrank p = 0.0239), and LIHC (HR = 1.52, logrank p = 0.0179, Figure 2A), and the similar results were shown in Figure 2C.