CD8+ T cells in the CT were more clustered (24.8 μm vs. 61.2 μm, p < 0.05) and located closer to CK+ tumor cells (39.4 μm vs. 104.6 μm, p < 0.05) in the response group than in the nonresponse group (Figure 4c). This evidence concerns the gene CD8A and neoplasm.