Microporous nanofibrous membranes have foundunique advantages in the development of highly sensitive colorimetricsensors due to the structural characteristic of extremely high specificsurface areas allowing increased loading of affinity elements, leadingto dramatically intensified colorimetric signals high enough for humaneye detection.26−28 The integration of both SARS-CoV-2 S-protein selectivebinding peptides and nanofibrous membranes could lead to the developmentof biosensors against COVID-19 with desired selectivity, sensitivity,and easy-to-use functions. The gene discussed is PROS1; the disease is COVID-19.