B3GNT3 and sexually transmitted disease: Among YMSM without STI, 23 genes were significantly (padj<0.1) differentially expressed between YMSM with and without HIV (Fig 4A), five of which (HSPB7, B3GNT3, AHNAK2, TMEM47, and COL28A1) were also among the 47 significant interaction genes identified.