Interestingly, our study showed lower levels of sVAP-1 in women with GDM as compared to the normoglycemic study population (366.73 ng/mL vs 428.34 ng/mL, respectively), suggesting a potential role of sVAP-1 in predicting the onset of GDM in the second and third trimesters of pregnancy. The gene discussed is SNAP47; the disease is gestational diabetes.